Viridian Women 40+ Multi 60caps Maximize

Viridian Women 40+ Multi 60caps

Woman 40+ Multi represents the best possible multivitamin for healthy aging and longevity available. More than just a multivitamin, Woman 40+ Multi blends high quality nutrients and plant extracts specifically to support healthy aging, optimal body weight, vision and heart health.

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60 Caps

R 545.58

INGREDIENTS: two vegetarian capsules provide:

Pomegranate (Punica granatum) Extract (40% Ellagic Acid) 100mg Red Grape Skin Extract (10% Resveratrol)                                                                                               100mg Green Coffee Bean Extract (45% Chlorogenic Acid)                                                                                      100mg Vitamin C          130mg

Magnesium (Ascorbate and citrate)                                            20mg

Seagreens® Kelp (Ascophyllum nodosum)                               100mg

Vitamin B5 (Calcium Pantothenate)                                           80mg

Beta-carotene (from Dunaliella Salina Algae)                                 5mg

Lutein Extract (5% Lutein)                                                        60mg

Calcium (Ascorbate and Citrate)                                               10mg Vitamin E Natural (D-Alpha Tocopherol Succinate)                                                                                 50IU Vitamin B6 (Pyridoxine HCl)           30mg

Vitamin B1 (Thiamine HCl)                                                        25mg

Potassium (Citrate)                                                                    10mg

Alpha Lipoic Acid                                                                       25mg

Vitamin B2 (Riboflavin)                                                              25mg

Vitamin B3 (Nicotinamide)                                                        25mg

Co Enzyme Q10                                                                        20mg

Zinc (Citrate)                                                                              5mg

Horsetail (Equisetum arvense) Extract (4:1) (2% Silica)               15mg Iron (Bisglycinate)              3mg

Choline (Bitartrate)                                                                      5mg

Selenium (Methionine)                                                                 55µg

Boron (Sodium Borate)                                                                 1mg

Inositol                                                                                           5mg

Vitamin D3                                                                                  10µg

Manganese (Citrate)                                                                      1mg

Copper (Citrate)                                                                           1mg

Vitamin K1                                                                                  50µg

Folic Acid                                                                                  400µg

Chromium (Picolinate)                                                                50µg

Iodine (Potassium Iodide)                                                             75µg

Molybdenum (Ammonium Molybdate)                                        50µg

Biotin                                                                                           50µg

Vitamin B12 (Methylcobalamin)                                                    25µg

In a base of alfalfa, spiruliana and bilberry

Woman 40+ Multi represents the best possible multivitamin for healthy aging and longevity available. More than just a multivitamin, Woman 40+ Multi blends high quality nutrients and plant extracts specifically to support healthy aging, optimal body weight, vision and heart health.

 

Suboptimal intakes of vitamins and minerals are remarkably common in the general population because of unhealthy eating, nutrient losses though food processing and storage and increased nutritional requirements due to factors such as alcohol use, chronic diseases and increasing age.1   For this reason, leading experts such as Harvard Medical School recommend a daily multivitamin as part of a healthy diet and lifestyle.2 3 There is a strong scientific rationale for the use of multivitamins as a safe and effective means of ensuring daily nutritional adequacy and promoting optimal health.4

 

  • ANTI-AGING - Resveratrol is a natural phytonutrient found in grape skins and wine with growing evidence for important health benefits.5 A number of human clinical studies suggest potential for the prevention of age-related diseases including heart disease, type-2 diabetes and cognitive decline.6 Clinical studies have demonstrated health benefits with daily supplementation of just 8-10 mg of high quality resveratrol daily.7 8 9 For example supplementation with 10 mg of resveratrol for 3-months significantly improved measures of cardiovascular health, including blood vessel relaxation, heart muscle function and cholesterol lowering effects.10 And in another study 10 mg of resveratrol daily was found to lower oxidative stress and improve insulin resistance within 4-weeks.11

 

Pomegranate has a long traditional association with longevity and modern research has confirmed potential benefits for preventing age related disease.12 A number of potential mechanisms for pomegranate observed health effects have been explored, in particular antioxidant and anti-inflammatory properties. Human clinical studies tend to suggest beneficial effects for cardiovascular health, type-2 diabetes, obesity and skin photoaging.13 14

 

  • DISEASE PREVENTION - Ensuring optimal daily intake of essential vitamins and minerals, along with additional anti-oxidant support has been suggested to be an important way to improve metabolism and prevent age related disease.15 More specifically low micronutrient intake can increase oxidative stress and accelerate DNA damage and mitochondrial decay subsequently giving rise to age-associated diseases; these processes could be offset by ensuring daily micronutrient intake with a multivitamin.16 17

 

  • WEIGHT MAINTENANCE - Green coffee bean extract (GCE) is a rich source of phytonutrients, most notably polyphenols occurring as chlorogenic acids, which have a variety of potential health benefits.18 GCE has been shown to have anti-obesity effects and regular use results in weight loss.19 A meta-analysis of the three clinical studies found an average weight loss of 2.5 kg at a dose of 180 mg to 200 mg daily.20 GCE has also been shown to improve blood vessel relaxation and reduce high blood pressure at a dose of 140 mg daily.21 22   Thus GCE has potential for cardiovascular health and maintenance of a healthy body weight.

 

Low intakes of vitamins and minerals may contribute to weight gain overtime by impairing fat metabolism.23   For example one study found that zinc, magnesium, vitamin C and vitamin E deficiency were risk factors of higher body weight and central obesity.24 And some studies have indicated that regular multivitamin use may be associated with a healthier body weight and better appetite control.25 26

  • EYE- HEALTH Lutein is a type of phytonutrient known as a carotenoid and imparts yellow or orange colour to various fruits and vegetables. A number of studies have shown that higher consumption of lutein rich foods or supplementation with pure lutein can protect skin and eyes from ultraviolet damage and reduce the risk of associated diseases.27 Lutein has shown particular promise for improving vision and reducing risk of age related macular degeneration.28 Dietary lutein concentrates in the retina of the eye and protects the macular from light damage as well as reducing oxidative stress and improving visual ability.29

 

The Age-Related Eye Disease study (AREDS) is a large-scale randomized controlled clinical trial that has provided the best evidence to date on vitamin and mineral supplements for eye health. The AREDS demonstrated that a combination of vitamins C, E, beta-carotene, zinc and copper resulted in a 25% risk reduction in progression to advanced AMD over 5 years.30 A multivitamin providing these nutrients may help maintain visual health alongside a healthy diet and lifestyle.31

Low dietary intakes of certain nutrients are particularly common and these play an important role in promoting optimal health, for example:

  • Suboptimal intakes of folic acid are very common and increasing folic acid intake through dietary supplements may correct megaloblastic anemia and improve blood levels of homocysteine, a risk factor for age related diseases.32

 

  • Vitamin D deficiency is a widespread problem and exacerbates osteopenia, osteoporosis, and fractures in adults and has been associated with increased risk of common illness including autoimmune disease, heart disease and infectious illness.33 To correct and prevent deficiency, experts recommend daily vitamin D supplements.34

 

  • Vitamin K plays an important role in protection against age related disease such as heart disease and osteoporosis.35 Intakes of vitamin K are commonly too low among children, adults and the elderly in the United Kingdom.36 37 38

 

  • Vitamin B12 deficiency is becomes more common with age and may have serious consequences.39 Deficiency and suboptimal intakes may have important implications for cognitive and mental health.40 Supplementation is the preferred means of correcting and preventing B12 deficiency.41

 

  • Suboptimal vitamin B6 status is associated with age related diseases such as impaired cognitive function, Alzheimer's disease and heart disease.42 The risk of low intakes of vitamin B6 increase with age and may also be low in vegetarian diets.43

 

  • Higher Vitamin E intake is associated with lower risk of chronic diseases such as heart disease, however fewer than 90% of people may be consuming the recommended daily amount.44 The Linus Pauling Institute recommends a daily supplementation with vitamin E to help combat oxidative stress, lower heart disease risk and promote wellbeing.45

 

  • Zinc deficiency is common with approximately 1 in 10 people not meeting their recommended daily intake. Even marginal zinc intakes may result in DNA damage and increased oxidative stress.46 Mild zinc deficiency may exacerbate immune, gastrointestinal, hormonal and mental illness and accelerate age related chronic degenerative diseases.47

 

  • Mild Iodine deficiency affects approximately 50% of continental Europe and mild iodine deficiency is very common in women living in the United Kingdom.48 49 50 51 52 53 Iodine deficiency can impair thyroid function.54

 

  • Coenzyme Q10 and Lipoic acid are potent anti-oxidant nutrients that have potential benefit for protection against age related degenerative diseases.55 56 Although not classically considered essential nutrients, deficiency can occur and use as dietary supplements may help maintain optimal health and wellbeing with age.57 58

 

Dosage: Two capsules once daily with food, or as recommended by a healthcare practitioner.

 

Contraindications and safety:

Resveratrol is well tolerated and there is no evidence for adverse effects.59 At a dose of 10 mg daily, resveratrol has been shown to improve blood glucose control so use with caution with diabetic medications (potential beneficial interaction).60

 

Green coffee bean extract may improve high blood pressure, so caution with anti-hypertensive medications (potential beneficial interaction).61

An expert panel from the National Institutes of Health reviewing the safety of Multivitamins concluded that there is no evidence of adverse effects and that multivitamins are unlikely to have any serious safety concerns.62 To ensure safety it is recommended that people using vitamin supplements inform their health care provider and use a reputable brand that meets regulatory quality standards.63

 

Potential applications: Daily nutritional support, optimal health, disease prevention, anti-aging, weight management, cardiovascular health, vision health, female health.

 

Useful links:

Take alongside Woman 40+ omega oil for optimal nutrition.

 

References

 

1 Fairfield KM, Fletcher RH (2002) Vitamins for chronic disease prevention in adults: scientific review. JAMA 287: 3116–3126

2 Willett WC (2001) Eat, Drink and be Healthy.New York,NY,USA: Simon & Schuster.

3 Ames BN. Increasing longevity by tuning

up metabolism: To maximize human health and lifespan, scientists must abandon outdated models of micronutrients. EMBO reports VOL 6 | SPECIAL ISSUE | 2005.

4 Ames BN. Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. PNAS. November 21, 2006, vol. 103 : no. 47; 17589–17594.

5 Nakata R, Takahashi S, Inoue H. Recent advances in the study on resveratrol. Biol Pharm Bull. 2012;35(3):273-9.

6 Timmers S, Auwerx J, Schrauwen P. The journey of resveratrol from yeast to human. Aging (AlbanyNY). 2012 Mar;4(3):146-58.

7 Tomé-Carneiro J, Gonzálvez M, Larrosa M, García-Almagro FJ, Avilés-Plaza F, Parra S, Yáñez-Gascón MJ, Ruiz-Ros JA, García-Conesa MT, Tomás-Barberán FA, Espín JC. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Mol Nutr Food Res. 2012 May;56(5):810-21.

8 Tomé-Carneiro J, Gonzálvez M, Larrosa M, Yáñez-Gascón MJ, García-Almagro FJ, Ruiz-Ros JA, Tomás-Barberán FA, García-Conesa MT, Espín JC. Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral blood mononuclear cells: a triple-blind, placebo-controlled, one-year clinical trial in patients with stable coronary artery disease. Cardiovasc Drugs Ther. 2013 Feb;27(1):37-48. doi: 10.1007/s10557-012-6427-8.

9 Tomé-Carneiro J, Gonzálvez M, Larrosa M, Yáñez-Gascón MJ, García-Almagro FJ, Ruiz-Ros JA, García-Conesa MT, Tomás-Barberán FA, Espín  JC. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease. Am J Cardiol. 2012 Aug 1;110(3):356-63.

10 Magyar K, Halmosi R, Palfi A, Feher G, Czopf L, Fulop A, Battyany I, Sumegi B, Toth K, Szabados E. Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease. Clin Hemorheol Microcirc. 2012;50(3):179-87. doi: 10.3233/CH-2011-1424.

11 Brasnyó P, Molnár GA, Mohás M, Markó L, Laczy B, Cseh J, Mikolás E, Szijártó IA, Mérei A, Halmai R, Mészáros LG, Sümegi B, Wittmann I. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br J Nutr. 2011 Aug;106(3):383-9

12 Medjakovic S, Jungbauer A. Pomegranate: a fruit that ameliorates metabolic syndrome. Food Funct. 2013 Jan;4(1):19-39.

13 Johanningsmeier SD, Harris GK. Pomegranate as a functional food and nutraceutical source. Annu Rev Food Sci Technol. 2011;2:181-201.

14 Jurenka JS. Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern Med Rev. 2008 Jun;13(2):128-44.

15 Ames BN. The metabolic tune-up: metabolic harmony and disease prevention. J Nutr. 2003 May;133(5 Suppl 1):1544S-8S.

16 Fenech MF. Dietary reference values of individual micronutrients and nutriomes for genome damage prevention: current status and a road map to the future. Am J Clin Nutr. 2010 May;91(5):1438S-1454S.

17AmesBN. Prevention of mutation, cancer, and other age-associated diseases by optimizing micronutrient intake. J Nucleic Acids. 2010 Sep 22;2010.

18 Williamson G, Dionisi F, Renouf M. Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages. Mol Nutr Food Res. 2011 Jun;55(6):864-73.

19 Shimoda H, Seki E, Aitani M. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complement Altern Med. 2006 Mar 17;6:9.

20 Onakpoya I, Terry R, Ernst E. The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials. Gastroenterol Res Pract. 2011;2011

21 Ochiai R, Jokura H, Suzuki A, Tokimitsu I, Ohishi M, Komai N, Rakugi H, Ogihara T. Green coffee bean extract improves human vasoreactivity. Hypertens Res. 2004 Oct;27(10):731-7.

22 Watanabe T, Arai Y, Mitsui Y, Kusaura T, Okawa W, Kajihara Y, Saito I. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin Exp Hypertens. 2006 Jul;28(5):439-49.

23 García OP, Long KZ, Rosado JL. Impact of micronutrient deficiencies on obesity. Nutr Rev. 2009 Oct;67(10):559-72.

24 Singh RB, et al. Association of low plasma concentrations of antioxidant vitamins, magnesium and zinc with high body fat per cent measured by bioelectrical impedance analysis in Indian men. Magnes Res. 1998 Mar;11(1):3-10.

25 Nachtigal MC, et al. Dietary supplements and weight control in a middle-age population. J Altern Complement Med. 2005 Oct;11(5):909-15. 26 Major GC, Doucet E, Jacqmain M, St-Onge M, Bouchard C, Tremblay A. Multivitamin and dietary supplements, body weight and appetite: results from a cross-sectional and a randomised double-blind placebo-controlled study. Br J Nutr. 2008 May;99(5):1157-67.

27 Shegokar R, Mitri K. Carotenoid lutein: a promising candidate for pharmaceutical and nutraceutical applications. J Diet Suppl. 2012 Sep;9(3):183-210.

28 Ma L, Dou HL, Wu YQ, Huang YM, Huang YB, Xu XR, Zou ZY, Lin XM. Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis. Br J Nutr. 2012 Feb;107(3):350-9.

29 Abdel-Aal el-SM, Akhtar H, Zaheer K, Ali R. Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health. Nutrients. 2013 Apr 9;5(4):1169-85.

30 The Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. Arch Ophthalmol. 2001;119:1417–36.

31 Sin HP, Liu DT, Lam DS. Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration. Acta Ophthalmol. 2013 Feb;91(1):6-11.

32 Dary O. Nutritional interpretation of folic acid interventions. Nutr Rev. 2009 Apr;67(4):235-44.

33 Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008 Apr;87(4):1080S-6S.

34 Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008 Apr;87(4):1080S-6S

35 McCann JC, Ames BN. Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? Am J Clin Nutr. 2009 Oct;90(4):889-907

36 Prynne CJ, Thane CW, Prentice A,WadsworthME.Intake and sources of phylloquinone (vitamin K(1)) in 4-year-old British children: comparison between 1950 and the 1990s. Public Health Nutr 2005;8: 171–80.

37 Thane CW, Bolton-Smith C, Coward WA. Comparative dietary intake and sources of phylloquinone (vitamin K1) among British adults in 1986–7 and 2000–1. Br J Nutr 2006;96:1105–15.

38 Thane CW, Paul AA, Bates CJ, Bolton-Smith C, Prentice A, Shearer MJ. Intake and sources of phylloquinone (vitamin K1): variation with socio- demographic and lifestyle factors in a national sample of British elderly people. Br J Nutr 2002;87:605–13.

39 Allen LH. How common is vitamin B-12 deficiency? Am J Clin Nutr. 2009 Feb;89(2):693S-6S.

40 Smith AD, Refsum H. Vitamin B-12 and cognition in the elderly. Am J Clin Nutr. 2009 Feb;89(2):707S-11S.

41 Andrès E, Vogel T, Federici L, Zimmer J, Kaltenbach G. Update on oral cyanocobalamin (vitamin B12) treatment in elderly patients. Drugs Aging. 2008;25(11):927-32.

42 Spinneker A, Sola R, Lemmen V, Castillo MJ, Pietrzik K, González-Gross M. Vitamin B6 status, deficiency and its consequences--an overview.

Nutr Hosp. 2007 Jan-Feb;22(1):7-24.

43 Food and Nutrition Board, Institute of Medicine. Vitamin B6. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B6, Vitamin B12, Pantothenic Acid, Biotin, and Choline.WashingtonD.C.: National Academies Press; 1998:150-195.

44 Traber MG, Frei B, Beckman JS. Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol. 2008 Feb;19(1):30-8.

45 Higdon J. Vitamin E. Linus Pauling Institute. Micronutrient Information Centre. Accessed on-line 18-02-2010.

46 Song Y et al. Dietary zinc restriction and repletion affects DNA integrity in healthy men. Am J Clin Nutr 2009;90:321–8.

47 Cummings JE, Kovacic JP. The ubiquitous role of zinc in health and disease. J Vet Emerg Crit Care (San Antonio). 2009 Jun;19(3):215-40.

48 Zimmermann MB. Symposium on 'Geographical and geological influences on nutrition': Iodine deficiency in industrialised countries. Proc Nutr Soc. 2010 Feb;69(1):133-43.

49 Bath S, Wright J, T aylor A, Walter A, Rayman MP. Iodine deficiency in pregnant women living in the South-East of theUK. Proc Nutr Soc 2010; 69: OC E6, E483.

50 Rayman MP, Sleeth M , Walter A, Taylor A. Iodine deficiency in UK women of child-bearing age. Proc Nutr Soc 2008; 67: E399. 51BathS, Walter A, T aylor A, Rayman MP. Iodine status ofUKwomen of childbearing age. J Hum Nutr Diet 2008; 21: 379–80.   52 Lazarus J, Smyth P. Iodine deficiency in theUKandIreland. Lancet 2008; 372: 888.

53 Kibirige MS, Hutchison S, Owen CJ, Delves HT. Prevalence of maternal dietary iodine insufficiency in the north east of England: implications for the fetus. Arch Dis Child Fetal Neonatal Ed. 2004 Sep;89(5):F436-9.

54 Zimmermann MB. Iodine deficiency. Endocr Rev. 2009 Jun;30(4):376-408. doi: 10.1210/er.2009-0011.

55 Villalba JM, Parrado C, Santos-Gonzalez M, Alcain FJ. Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations. Expert Opin Investig Drugs. 2010 Apr;19(4):535-54.

56 Rochette L, Ghibu S, Richard C, Zeller M, Cottin Y, Vergely C. Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential. Mol Nutr Food Res. 2013 Jan;57(1):114-25.

57 Potgieter M, Pretorius E, Pepper MS. Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation. Nutr Rev. 2013 Mar;71(3):180-8.

58 Gorąca A, Huk-Kolega H, Piechota A, Kleniewska P, Ciejka E, Skibska B. Lipoic acid - biological activity and therapeutic potential. Pharmacol Rep. 2011;63(4):849-58.

59 Edwards JA, Beck M, Riegger C, Bausch J. Safety of resveratrol with examples for high purity, trans-resveratrol, resVida(®). Ann N Y Acad Sci. 2011 Jan;1215:131-7.

60 Brasnyó P, Molnár GA, Mohás M, Markó L, Laczy B, Cseh J, Mikolás E, Szijártó IA, Mérei A, Halmai R, Mészáros LG, Sümegi B, Wittmann I. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br J Nutr. 2011 Aug;106(3):383-9.

61 Watanabe T, Arai Y, Mitsui Y, Kusaura T, Okawa W, Kajihara Y, Saito I. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin Exp Hypertens. 2006 Jul;28(5):439-49.

62 National Institutes of Health State-of-the-Science Conference Statement: Multivitamin/Mineral Supplements and Chronic Disease Prevention. Ann Intern Med. 2006;145:364-371.

63 Position of the American Dietetic

Disclaimer: All information contained on this website is for information only and should not be used to diagnose, prevent, treat or cure any disease, health or medical condition. The products (food supplements) are not intended to diagnose, prevent, treat or cure any health or medical condition. Do not exceed stated dose or use with prescribed medication unless advised by a doctor or medical practitioner. Do not take if pregnant or lactating. Keep out of reach of children. Consult doctor for all medical advice.