Viridian Enhanced Rhodiola Complex Maximize

Viridian Enhanced Rhodiola Complex

The adaptogenic herbs Ashwagandha, Siberian ginseng, Schisandra, Liquorice and Rhodiola have a long history of traditional use for restoring energy, mood, vitality and building resistance to chronic stress. Clinical studies have shown they can improve a wide range of stress related symptoms.

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30 Caps
90 Caps

R 251.28

Enhanced Rhodiola Complex Veg Caps

A high-potency synergistic blend of the best studied adaptogens. INGREDIENTS: one vegetarian capsule provides:

Siberian ginseng root extract                                                    160mg

Ashwaghandha extract                                                             125mg

Licorice root extract                                                                100mg

Schisandra berry extract                                                           100mg

Rhodiola rosea root extract                                                         83mg

The adaptogenic herbs Ashwagandha, Siberian ginseng, Schisandra, Liquorice and Rhodiola have a long history of traditional use for restoring energy, mood, vitality and building resistance to chronic stress. Indeed, a number of modern clinical studies have shown they can improve a wide range of stress related symptoms including chronic fatigue, anxiety, depression, poor concentration and physical and emotional burnout as well as enhance performance under stress.

 

Ashwagandha (Withania somnifera) – Native to India and used as part of traditional Ayurvedic medicine, is also known as winter cherry or Indian ginseng. In Ayurveda, it is classified as a rasayana (rejuvenating) and is used to promote physical and mental health, rejuvenate the body in debilitated conditions and increase longevity.1

 

  • Stress – A double-blind, placebo control trial looked into the benefits of supplementing with Ashwagandha root extract in reducing stress and anxiety and improving overall wellbeing in adults. Results showed a reduction in stress questionnaire results compared to placebo and a significant reduction in cortisol levels.2 Another study found that supplementing with 125mg of a high quality Ashwagandha extract once to twice daily for 60-days significantly reduced symptoms of stress and anxiety.3

 

Ashwagandha also significantly decreased the stress hormone cortisol (see image 2), the inflammatory marker C-reactive protein and the cardiovascular health markers pulse rate and blood pressure. In addition there was a significant increase in dehydroepiandrosterone sulfate (DHEAS) and  haemoglobin, indicating a healthier stress response and improved red blood cell formation and energy, respectively.

  • Anxiety – In a clinical study Ashwagandha was used as part of an integrative treatment plan for anxiety sufferers along with treatments such as dietary changes and deep breathing exercises. The results of this study found that – along side diet and lifestyle changes - Ashwagandha was able to help significantly relive anxiety symptoms.4

 

  • Stress-related male infertility - Stress has been shown to reduce sperm quality and fertility in men, so a clinical study examined the effects of Ashwagandha to reduce stress and improve male infertility.5 After 3-months of treatment with Ashwagandha there was a decrease in stress, improved level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients.

 

  • Heart health - The benefits of ashwagandha also cover cardiovascular health. Studies have found when supplementing with ashwagandha short term and long term with up to 3 grams daily, benefits were seen including a reduction in blood glucose, which was comparable to that of an oral hypoglycaemic drug, a significant decrease in serum cholesterol and triglycerides and an increase in urine volume indicating diuretic properties.6 Another study also found an improvement in haeomoglobin and red blood cell count as well as cholesterol levels.7

 

Siberian Ginseng (Eleutherococcus senticosus) Has a long history of traditional use in Chinese medicine and is well known to have adaptogenic effects.8   Siberian ginseng has been famously used by Russian astronauts and athletes to improve performance under extreme physical and mental demands.

 

  • Stress - In a group of 18-30 year old students Siberian ginseng was shown to improve stress adaption by reducing cardiovascular reactivity to stress (resulting in a 40% reduction in heart rate response). The same study also found that Siberian ginseng reduced stress-induced blood pressure elevation by 60% in women, but not in men.9

 

  • Chronic fatigue - A clinical study of Siberian ginseng in people with chronic fatigue syndrome found a modest benefit in participants with less-severe fatigue. In this study a dose of approximately 2000 to 4000 mg equivalent dry root per day was given over a period of 2- months.10

 

  • General wellbeing - To see if Siberian ginseng could improve general health and wellbeing a group of elderly individuals (average age 65 years) were given Siberian ginseng over a  period of 8-weeks. After 4 weeks, higher scores in social functioning scales were observed in patients using Siberian ginseng, however these differences did not persist to the 8-week time point.11

 

  • Physical performance – Supplementation with Siberian ginseng for a period of 8-weeks was shown to improve endurance capacity, elevated cardiovascular functions and changes in metabolism to spare glycogen in trained athletes.12

 

  • Depression – Siberian ginseng has been shown to have comparable effects to medication for depressive symptoms. In subjects with bipolar disorder Siberian ginseng supplementation for 6-weeks was slightly more effective than anti-depressant medication (fluoxetine) and had a better safety profile with fewer adverse events.13 And in another study of people suffering from moderate depression Siberian ginseng was as effective as the anti-depressant medication imipramine.14

 

Schisandra Berry (Schisandra chinensis) – Native to the forests of Northern China and Russia and is frequently used in traditional Chinese medicine to restore energy and vitality or “Qi.” It is sometimes called the ‘five flavour berry’ as the berries contain all five flavours referred to in Chinese medicine, and is therefore considered a tonic.

 

  • Stress – A large number of early clinical studies conducted in Russia explored the adaptogenic effects of Schisandra in a very wide range of illness. These clinical trials reported positive effects of supplementation in conditions such as physical fatigue, depression, mental fatigue, schizophrenia, alcoholism, cardiovascular illness, digestive illness and increased risk of infections.15

 

  • Energy and mood – In a clinical study of people suffering from weakness and depression the administration of Schisandra berry for 40 days resulted in stimulation of the central nervous system in every participant. End point results showed improved energy levels and physical activity, reduction in fatigue, improved mood and normalisation of sleep in participants with depression and weakness.16

 

Rhodiola (Rhodiola rosea) - also known as arctic root or golden root is indigenous to the polar arctic regions of eastern Siberia and has enjoyed a long and traditional use in Russia, China and Scandinavia. Rhodiola is now a very popular herb for improving adaptation to stress worldwide.

 

  • Stress – Rhodiola enhances mental and physical performance under stress. In physicians performing night duty, supplementation with Rhodiola over 2-weeks improved measures of cognitive performance and reduced general fatigue.17 In students undergoing an examination period, Rhodiola use over 20-days improved mental performance, physical fitness, general well-being and reduced mental fatigue.18

 

  • Fatigue A number of clinical studies have shown that supplementation with Rhodiola can relieve fatigue and improve energy.19 For example, in people suffering from severe stress related fatigue and burnout, Rhodiola supplementation for 28-days was found to improve mood, fatigue and nervous system function. It was concluded that Rhodiola “exerts an anti- fatigue effect that increases mental performance, particularly the ability to concentrate, and decreases cortisol response to awakening stress in burnout patients with fatigue syndrome.20”
 
  • Anxiety and depression – In people with generalized anxiety disorder Rhodiola reduced anxiety levels with comparable effects to anti-anxiety medications within 10-weeks.21 And in people with mild to moderate depression Rhodiola significantly reduced depressive symptoms over a 6-week period.22

 

  • Physical performance –– Rhodiola has long been used for its ability to enhance performance and some, but not all, studies have suggested Rhodiola can improve physical fitness. For example, a study looking into Rhodiola found that supplementation for 4-weeks was able to improve endurance exercise ability.23

 

Licorice (Glycyrrhiza glabra) Native to southern Europe and Asia, and has been used as a food in medicine since prehistoric times. As well as its use as flavouring in confectionary, Licorice is still popularly used as a medicine.

 

  • Adrenal fatigue – Licorice is traditionally viewed as an adrenal tonic, indeed research has shown it has a “cortisol sparing” effect due to its ability to reduce and slow down cortisol breakdown. This occurs by the ability of and active component of Licorice, glycyrrhizin, to inhibit the 11-beta-hydroxysteroid-dehydrogenase enzyme, which metabolises cortisol. This may be useful in those experiencing chronic stress and unable to maintain a healthy stress response.24 In Addison’s disease – a condition characterised by adrenal insufficiency and low cortisol levels – Licorice has been shown to increase cortisol availability.25

 

 

  • Chronic fatigue – A popular use of Licorice is to combine it with other adaptogenic herbs for the relief of chronic fatigue syndrome. There is one published case report of a patient suffering from chronic fatigue syndrome who experienced improved physical and mental stamina when supplementing with Licorice.26

 

Dosage

 

Take one to two capsules daily with food. For children 7-12 years, one capsule daily. Not recommended under 7-years unless advised by a health care professional.

 

 

Potential applications

 

Adrenal fatigue, burnout, stress, anxiety, weakness, fatigue, tiredness, fibromyalgia and chronic fatigue syndrome.

 

Contraindications

 

Do not take if you are pregnant or breast-feeding.

Persons who experience hypertension, coronary spasm and fluctuations in arterial pressure should only use under supervision.

 

Caution should be expressed in those with bipolar disorder.

 

Interactions

 

Do not take alongside antihypertensives, warfarin, beta blockers or anti-arrythimatic agents. Avoid long-term use of licorice with diuretic medication unless under professional supervision.

 

 

References 

1 Kulkarni SK, Dhir A. Withania somnifera: an Indian ginseng. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1093-105.

2 Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and

efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62.

3 Auddy B, et al. A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically

Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study. Journal of the American Nutraceutical Association. 2008;11(1):50-56.

4 Cooley K, Szczurko O, Perri D, Mills EJ, Bernhardt B, Zhou Q, Seely D, 2009. Naturopathic care for anxiety: a randomized

controlled trial. Aug 31;4(8):e6628.

5 Mahdi AA, et al. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility. Evid Based Complement Alternat Med. 2009 Sep 29. [Epub ahead of print] PubMed PMID: 19789214; PubMed Central PMCID: PMC3136684.

6 Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol. 2000 Jun;38(6):607-9. PubMed PMID: 11116534.

7 Bone K. Clinical Applications of Ayurvedic and Chinese Herbs. Monographs for the Western Herbal Practitioner.

Australia: Phytotherapy Press; 1996:137-14.

8 Huang L, Zhao H, Huang B, Zheng C, Peng W, Qin L. Acanthopanax senticosus: review of botany, chemistry and pharmacology. Pharmazie. 2011 Feb;66(2):83-97.

9 Facchinetti F, Neri I, TarabusiM(2002) Eleutherococcus senticosus reduces cardiovascular stress response in healthy

subjects: a randomized, placebocontrolled trial. Stress Health 18: 11–17.

10 Hartz AJ, Bentler S, Noyes R, et al. Randomized controlled trial of Siberian ginseng for chronic fatigue. Psychol Med. 2004;34(1):51-61.

11 Cicero AF, Derosa G, Brillante R, Bernardi R, Nascetti S, Gaddi A. Effects of Siberian ginseng (Eleutherococcus senticosus

maxim.) on elderly quality of life: a randomized clinical trial. Arch Gerontol Geriatr Suppl. 2004;(9):69-73.

12 Kuo J, Chen KW, Cheng IS, Tsai PH, Lu YJ, Lee NY. 2010. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human. Chin J Physiol. 2010 Apr 30;53(2):105-11. 13 Weng S, Tang J, Wang G, et al. Comparison of the addition of Siberian Ginseng (Acanthopanax senticosus) versus

fluoxetine to lithium for the treatment of bipolar disorder in adolescents: a randomized. Curt Ther Res Clin Exp 2007;68:280–90.

14 S Weng, Z Cheng, H Wang. An open-label study of capsule Acanthopanax senticosus for treatment of depression in

patients. Hubei Journal of Chinese Traditional Medicine, 6 (2001), pp. 8–9.

15 Panossian A, Wikman G. Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine. J Ethnopharmacol. 2008 Jul 23;118(2):183-212.

16 Panossian AG. Adaptogens in mental and behavioral disorders. Psychiatr Clin North Am. 2013 Mar;36(1):49-64.

17 V. Darbinyan, A. Kteyan, A. Panossian, E. Gabrielian, G. Wikman, H. Wagner. 2000. Rhodiola rosea in stress induced  fatigue — A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental

performance of healthy physicians during night duty. PhytomedicineVolume 7, Issue 5, October 2000, Pages 365–371.

18 A.A. Spasov, G.K. Wikman, V.B. Mandrikov, I.A. Mironova, V.V. Neumoin. A double-blind, placebo-controlled pilot study

of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. Volume 7, Issue 2, April 2000, Pages 85– 89.

19 Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and

clinical efficacy. Phytomedicine. 2010;17(7):481-493.

20 Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta

Med. 2009 Feb;75(2):105-12.

21 Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med. 2008 Mar;14(2):175-80.

22 Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian A. Clinical trial of Rhodiola rosea L. extract

SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. 2007;61(5):343-8.

23 K. De Bock, B, O Eijnde, M. Ramaekers, P. Hespel. 2004. Acute Rhodiola rosea intake can improve endurance exercise performance. International journal of sport nutrition and exercise metabolism. 14, 298-307.

24 L. Braun, M. Cohen. 2010. Herbs and Natural supplements – An evidence based guide. 3rd edition. Australia. Elsevier.

25 Methlie P, Husebye EE, Hustad S, Lien EA, Lovas K. Grapefruit juice and licorice Increase cortisol availability in patients with Addison’s disease. Eur J Endocrinol. 2011;165(5):761-769. doi:10.1530/EJE-11-0518.

26 Baschetti R. Chr

Disclaimer: All information contained on this website is for information only and should not be used to diagnose, prevent, treat or cure any disease, health or medical condition. The products (food supplements) are not intended to diagnose, prevent, treat or cure any health or medical condition. Do not exceed stated dose or use with prescribed medication unless advised by a doctor or medical practitioner. Do not take if pregnant or lactating. Keep out of reach of children. Consult doctor for all medical advice.